Elevated serum zonulin is associated with high attack frequency in hereditary angioedema: providing insight into the gut–angioedema axis

Abstract Background Zonulin is a key regulator of epithelial barrier permeability and has been implicated in barrier dysfunction across various inflammatory conditions. To elucidate the potential role of intestinal permeability in HAE, this study investigated serum zonulin levels and evaluated their...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Ragıp Fatih Kural, Kasım Okan, Onurcan Yildirim, Elif Azarsiz, Serpil Akten, Reyhan Gumusburun, Ceyda Tunakan Dalgic, Nihal Mete Gokmen
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2026-02-01
Schriftenreihe:	Orphanet Journal of Rare Diseases
Schlagworte:	Hereditary angioedema Zonulin Biomarker Intestinal permeability Psychological burden
Online-Zugang:	https://doi.org/10.1186/s13023-026-04286-6
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