SHP2 promotes the epithelial-mesenchymal transition in triple negative breast cancer cells by regulating β-catenin

Abstract Purpose Growing evidence suggests that the tyrosine phosphatase SHP2 is pivotal for tumor progression. Triple-negative breast cancer (TNBC) is the most lethal subtype of breast cancer, characterized by its high recurrence rate, aggressive metastasis, and resistance to chemotherapy. Understa...

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Үндсэн зохиолчид:	Shihan Qian, Jingjing Zhu, Qing Han, Huang Cheng, Huaibin Zhou
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Springer 2025-01-01
Цуврал:	Journal of Cancer Research and Clinical Oncology
Нөхцлүүд:	Epithelial-mesenchymal transition Triple negative breast cancer SHP2 β-catenin GSK3β AKT
Онлайн хандалт:	https://doi.org/10.1007/s00432-025-06097-x
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!