Cap-Specific m⁶Am Methyltransferase PCIF1/CAPAM Regulates mRNA Stability of <i>RAB23</i> and <i>CNOT6</i> through the m⁶A Methyltransferase Activity

Chemical modifications of cellular RNAs play key roles in gene expression and host defense. The cap-adjacent <i>N</i>⁶,2′-<i>O</i>-dimethyladenosine (m⁶Am) is a prevalent modification of vertebrate and viral mRNAs and is catalyzed by the newly discovered <i>N</i>⁶ me...

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主要な著者:	Ai Sugita, Ryoya Kano, Hiroyasu Ishiguro, Natsuki Yanagisawa, Soichiro Kuruma, Shotaro Wani, Aki Tanaka, Yoshiaki Tabuchi, Yoshiaki Ohkuma, Yutaka Hirose
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2024-10-01
シリーズ:	Cells
主題:	gene expression mRNA modifications mRNA stability transcription mRNA cap m<sup>6</sup>A
オンライン･アクセス:	https://www.mdpi.com/2073-4409/13/20/1689
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