Immortalization of mouse myogenic cells can occur without loss of p16^{<it>INK4a</it>}, p19^<it>ARF</it>, or p53 and is accelerated by inactivation of Bax

<p>Abstract</p> <p>Background</p> <p>Upon serial passaging of mouse skeletal muscle cells, a small number of cells will spontaneously develop the ability to proliferate indefinitely while retaining the ability to differentiate into multinucleate myotubes. Possible gene changes that could underlie my...

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Autors principals:	Kravetz Amanda J, Kostek Christine A, Girgenrath Mahasweta, Malowitz Jonathan, Nowak Jonathan A, Dominov Janice A, Miller Jeffrey
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2004-01-01
Col·lecció:	BMC Cell Biology
Matèries:	apoptosis Bax myoblast muscle fiber p16<sup><it>INK4a</it></sup> p19<sup><it>ARF</it></sup> p53
Accés en línia:	http://www.biomedcentral.com/1471-2121/5/1
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