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In Vitro Treatment with Ganciclovir Restores the Functionality of Exhausted T Cells from Cancer Patients

Background: Human cytomegalovirus (CMV) is a lifelong, often asymptomatic infection, with the virus maintained in latently infected myeloid cells. Patients receiving chemotherapy for cancer are at high risk of reactivation of latent CMV, which may further contribute to host immune exhaustion, ultima...

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Principais autores: Chia-Ming Chang, Chien-Liang Wu, I-Hsuan Chen, Kate Hsu, Hsin-Tsung Ho, I-Pin Chuang, Yen-Ta Lu
Formato: Artigo
Idioma:Inglês
Publicado em: Taiwan Society of Geriatric Emergency and Critical Medicine (TSGECM) 2013-09-01
coleção:International Journal of Gerontology
Assuntos:
cancer
CMV reactivation
cytomegalovirus
ganciclovir
immune exhaustion
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S187395981200155X
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