CYP2D6 polymorphisms and endoxifen concentration in Chinese patients with breast cancer

Abstract Background The plasma concentration of endoxifen, the active metabolite of tamoxifen, might be affected by different CYP2D6 genotypes in patients with breast cancer, but solid evidence is still lacking in Asian patients. This prospective study aimed to investigate the relationship between C...

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Huvudupphov:	Cong Xue, Wei Yang, Anqi Hu, Caiyun He, Hai Liao, Meiting Chen, Xin An, Shusen Wang, Zhongyu Yuan, Fei Xu, Jun Tang, Haifeng Li, Su Li, Jianyong Shao, Yanxia Shi
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	BMC 2025-03-01
Serie:	BMC Cancer
Ämnen:	Breast cancer CYP2D6 Endoxifen Plasma concentration Tamoxifen
Länkar:	https://doi.org/10.1186/s12885-025-13791-z
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