E. coli TraR allosterically regulates transcription initiation by altering RNA polymerase conformation

TraR and its homolog DksA are bacterial proteins that regulate transcription initiation by binding directly to RNA polymerase (RNAP) rather than to promoter DNA. Effects of TraR mimic the combined effects of DksA and its cofactor ppGpp, but the structural basis for regulation by these factors remain...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	James Chen, Saumya Gopalkrishnan, Courtney Chiu, Albert Y Chen, Elizabeth A Campbell, Richard L Gourse, Wilma Ross, Seth A Darst
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	eLife Sciences Publications Ltd 2019-12-01
Цуврал:	eLife
Нөхцлүүд:	cryo-electron microscopy RNA polymerase transcription initiation TraR
Онлайн хандалт:	https://elifesciences.org/articles/49375
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!