Convenient Synthesis and Biological Evaluation of Modafinil Derivatives: Benzhydrylsulfanyl and Benzhydrylsulfinyl [1,2,3]triazol-4-yl-methyl Esters

Simple synthesis and biological activities of modafinil derivatives are described. The key reactions include condensation of acid and propargyl alcohol, subsequent 1,3-dipolar cycloaddition reaction of alkynes and (3-azido-propyl)cyclohexane or (4-azido-butyl)benzene in the presence of sodium ascorb...

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Principais autores:	Seikwan Oh, Mankil Jung, Eunyoung Lim, Jee-Young Son, Yeonju Lee, Jae-Chul Jung
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2011-12-01
coleção:	Molecules
Assuntos:	benzhydrylsulfanyl-[1,2,3]triazol-4-yl-methyl ester benzhydrylsulfinyl-1,2,3]triazol-4-yl-methyl ester NO-generation condensation 1,3-dipolar cycloaddition reaction
Acesso em linha:	http://www.mdpi.com/1420-3049/16/12/10409/
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