Perturbing local steroidogenesis to improve breast cancer immunity
Abstract Breast cancer, particularly triple-negative breast cancer (TNBC), evades the body’s immune defences, in part by cultivating an immunosuppressive tumour microenvironment. Here, we show that suppressing local steroidogenesis can augment anti-tumour immunity against TNBC. Through targeted meta...
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| Hlavní autoři: | , , , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Portfolio
2025-04-01
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| Edice: | Nature Communications |
| On-line přístup: | https://doi.org/10.1038/s41467-025-59356-3 |
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