Lung-specific MCEMP1 functions as an adaptor for KIT to promote SCF-mediated mast cell proliferation

Abstract Lung mast cells are important in host defense, and excessive proliferation or activation of these cells can cause chronic inflammatory disorders like asthma. Two parallel pathways induced by KIT–stem cell factor (SCF) and FcεRI–immunoglobulin E interactions are critical for the proliferatio...

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Autors principals:	Youn Jung Choi, Ji-Seung Yoo, Kyle Jung, Logan Rice, Dokyun Kim, Violetta Zlojutro, Matthew Frimel, Evan Madden, Un Yung Choi, Suan-Sin Foo, Younho Choi, Zhongyi Jiang, Holly Johnson, Mi-Jeong Kwak, Seokmin Kang, Brian Hong, Gil Ju Seo, Stephanie Kim, Shin-Ae Lee, Samad Amini-Bavil-Olyaee, Hadi Maazi, Omid Akbari, Kewal Asosingh, Jae U. Jung
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2023-04-01
Col·lecció:	Nature Communications
Accés en línia:	https://doi.org/10.1038/s41467-023-37873-3
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