Transcription factor TFII-I fine tunes innate properties of B lymphocytes

The ubiquitously expressed transcription factor TFII-I is a multifunctional protein with pleiotropic roles in gene regulation. TFII-I associated polymorphisms are implicated in Sjögren’s syndrome and Lupus in humans and, germline deletion of the Gtf2i gene in mice leads to embryonic lethality. Here...

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Principais autores:	Amit Singh, Mary Kaileh, Supriyo De, Krystyna Mazan-Mamczarz, Dashzeveg Bayarsaihan, Ranjan Sen, Ananda L. Roy
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2023-01-01
Serija:	Frontiers in Immunology
Teme:	B cell Gtf2i FO and MZ B cells innate and adaptive immunity chromatin accessibility
Online dostop:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1067459/full
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