Comparative performance analysis of neoepitope prediction algorithms in head and neck cancer

BackgroundMutations in cancer cells can result in the production of neoepitopes that can be recognized by T cells and trigger an immune response. A reliable pipeline to identify such immunogenic neoepitopes for a given tumor would be beneficial for the design of cancer immunotherapies. Current metho...

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Hlavní autoři:	Leila Y. Chihab, Julie G. Burel, Aaron M. Miller, Luise Westernberg, Brandee Brown, Jason Greenbaum, Michael J. Korrer, Stephen P. Schoenberger, Sebastian Joyce, Young J. Kim, Zeynep Koşaloğlu-Yalçin, Bjoern Peters
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2025-03-01
Edice:	Frontiers in Immunology
Témata:	cancer neoepitope prediction neoepitope screening bioinformatics immunogenicity
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1494453/full
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