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New insights into the cellular temporal response to proteostatic stress

Maintaining a healthy proteome involves all layers of gene expression regulation. By quantifying temporal changes of the transcriptome, translatome, proteome, and RNA-protein interactome in cervical cancer cells, we systematically characterize the molecular landscape in response to proteostatic chal...

Deskribapen osoa

Gorde:
Egile Nagusiak: Justin Rendleman, Zhe Cheng, Shuvadeep Maity, Nicolai Kastelic, Mathias Munschauer, Kristina Allgoewer, Guoshou Teo, Yun Bin Matteo Zhang, Amy Lei, Brian Parker, Markus Landthaler, Lindsay Freeberg, Scott Kuersten, Hyungwon Choi, Christine Vogel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications Ltd 2018-10-01
Saila:eLife
Gaiak:
proteostasis
unfolded protein response
energy metabolism
stress response
translation regulation
central dogma
Sarrera elektronikoa:https://elifesciences.org/articles/39054
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