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Simvastatin, but not pravastatin, inhibits the proliferation of esophageal adenocarcinoma and squamous cell carcinoma cells: a cell-molecular study

Abstract Background and objective Long-term statin therapy has been shown to protect against several cancers, including esophageal cancer (EC). While the mechanisms underlying this effect are not clear. We investigated the effect of hydrophobic simvastatin and hydrophilic pravastatin on the prolifer...

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Auteurs principaux: Yan Chen, Li-Bin Li, Jun Zhang, Du-Peng Tang, Jing-Jing Wei, Ze-Hao Zhuang
Format: Artigo
Langue:Inglês
Publié: BMC 2018-12-01
Collection:Lipids in Health and Disease
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Accès en ligne:http://link.springer.com/article/10.1186/s12944-018-0946-7
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