LY294002 Inhibits Intermediate Conductance Calcium-Activated Potassium (KCa3.1) Current in Human Glioblastoma Cells

Glioblastomas (GBs) are among the most common tumors with high malignancy and invasiveness of the central nervous system. Several alterations in protein kinase and ion channel activity are involved to maintain the malignancy. Among them, phosphatidylinositol 3-kinase (PI3K) activity and intermediate...

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Ngā kaituhi matua:	Concetta Caglioti, Federico Palazzetti, Lorenzo Monarca, Raffaele Lobello, Maria Rachele Ceccarini, Rossana Giulietta Iannitti, Roberta Russo, Francesco Ragonese, Chiara Pennetta, Antonella De Luca, Michela Codini, Bernard Fioretti
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Frontiers Media S.A. 2022-01-01
Rangatū:	Frontiers in Physiology
Ngā marau:	LY294002 (PI3K inhibitor) KCa3.1 (intermediate-conductance Ca2+-activated K+ channel) glioblastoma histamine (H1) receptor calcium homeostasis chemio and radioresistance
Urunga tuihono:	https://www.frontiersin.org/articles/10.3389/fphys.2021.790922/full
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!