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Microstructural and functional abnormalities of the locus coeruleus in freezing of gait in Parkinson's disease

Objective: The loss of locus coeruleus (LC)-norepinephrine system may contribute to freezing of gait (FOG) in Parkinson's disease (PD), but free-water (FW) imaging has not been applied to investigate LC microstructural degeneration in FOG. This study was to investigate the role of the LC-norepinephr...

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Bibliografische Detailangaben
Hauptverfasser: Huimin Sun, Caiting Gan, Xingyue Cao, Yongsheng Yuan, Heng Zhang, Chenhui Wan, Jiaxin Shi, Xufeng Wang, Youyong Kong, Tao Feng, Kezhong Zhang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2025-05-01
Schriftenreihe:Neurobiology of Disease
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Online-Zugang:http://www.sciencedirect.com/science/article/pii/S0969996125000841
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