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A novel murine model of Sjögren’s disease using lacrimal autoantigen

PurposeSjögren’s disease (SjD) is a group of chronic autoimmune diseases primarily targeting exocrine glands, including the lacrimal glands (LG). Involvement of the lacrimal glands leads to severe dry eye, also known as Sjögren’s disease-associated dry eye (SjD-DE). Current, available animal models...

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Principais autores: Siyuan Li, Shan Liu, Yaqiong Li, Peng Zhang, Fengyang Lei, Lei Tian, Ying Jie
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2026-02-01
סדרה:Frontiers in Immunology
נושאים:
autoimmune
dry eye
inflammation
lacrimal gland
Sjögren’s disease
גישה מקוונת:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1586519/full
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