Mechanical Stress Triggers Premature Senescence in Cardiac Fibroblasts

Abstract The cardiovascular system functions under continuous cyclic mechanical stretch, with disruptions in mechanical and biochemical signals contributing to disease progression. In cardiovascular disorders, these disruptions activate cardiac fibroblasts (CFs) and promote cellular senescence, yet...

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Үндсэн зохиолчид:	Stephanie E. Schneider, Adrienne K. Scott, Katie M. Gallagher, Emily Y. Miller, Soham Ghosh, Corey P. Neu
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Wiley 2025-12-01
Цуврал:	Advanced Science
Нөхцлүүд:	cellular senescence mechanical stress mechanosensitivity nuclear integrity
Онлайн хандалт:	https://doi.org/10.1002/advs.202513314
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!