MMAE-loaded PLGA nanomedicine with improved biosafety to achieve efficient antitumor treatment

Monomethyl auristatin E (MMAE) is a derivative of the marine peptide Dolastatin 10, which has therapeutic effects against various cancers according to its antimitotic activity in multiple clinical trials. The antibody drug conjugate (ADC) of MMAE is currently used in clinical practice. However, the...

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Bibliografske podrobnosti

Principais autores:	Changqiang Xie, Yan Wang, Zhenzhen Cai, Jianghai Du, Zhengyu Chen, Junjie Wang, Xingzhou Peng
Format:	Artigo
Jezik:	Inglês
Izdano:	World Scientific Publishing 2024-03-01
Serija:	Journal of Innovative Optical Health Sciences
Teme:	Monomethyl auristatin E poly (lactic-co-glycolic acid) nanoparticles sustained release chemotherapy immunogenic cell death
Online dostop:	https://www.worldscientific.com/doi/10.1142/S1793545823500244
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