Role of stable hydrogen isotope variations in water for drug dissolution managing

In the present work, we provide the results of defining by utilizing Laser diffraction spectroscopy, the kinetic isotopic effect of solvent and constant of dissolution rate κ, s−1 of аn active pharmaceutical ingredient (API) in water with a different content of a stable 21H_2^1{\rm{H}} isotope on th...

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Autors principals:	Uspenskaya Elena V., Pleteneva Tatyana V., Syroeshkin Anton V., Kazimova Ilaha V., Elizarova Tatyana E., Odnovorov Artem I.
Format:	Artigo
Idioma:	Inglês
Publicat:	Medical University of Lublin 2020-06-01
Col·lecció:	Current Issues in Pharmacy and Medical Sciences
Matèries:	kinetics dissolving laser diffraction spectroscopy deuterium depleted water (ddw) kinetic isotope effect (kies) water clusters antibacterial neuroprotective drugs
Accés en línia:	http://www.degruyter.com/view/j/cipms.2020.33.issue-2/cipms-2020-0017/cipms-2020-0017.xml?format=INT
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