The biological effects of CRP are not attributable to endotoxin contamination: evidence from TLR4 knockdown human aortic endothelial cells

C-reactive protein (CRP) is the prototypic marker of inflammation and a strong predictor of cardiovascular events in humans. There are questions regarding the validity of the biological effects reported for CRP, in spite of adherence to rigorous control measures minimizing endotoxin [lipopolysacchar...

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Detalhes bibliográficos

Principais autores:	Mohan R. Dasu, Sridevi Devaraj, Terry W. Du Clos, Ishwarlal Jialal
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2007-03-01
coleção:	Journal of Lipid Research
Assuntos:	acute-phase reactant cytokines inflammation lipopolysaccharide Toll like receptor 4 C-reactive protein
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0022227520432262
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