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Three-dimensional cardiac organoid formation accelerates the functional maturation of human induced pluripotent stem cell-derived cardiomyocytes

Background Human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes (CMs) offer a promising source for heart disease modeling and drug screening. Recent developments in organoid technology have made it possible to study how hiPSC-derived CMs interact together, and this culture system mimic...

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Principais autores: Hanbyeol Lee, Jeong Suk Im, Da Bin Choi, Jieun An, Su-Bin Kim, Seunghee Yeon, Seulgi Yoon, Dong-Hun Woo
Format: Artigo
Sprog:Inglês
Udgivet: The Organoid Society 2022-05-01
Serier:Organoid
Fag:
cardiomyocytes
cardiac organoid
human induced pluripotent stem cells
differentiation
maturation
Online adgang:http://j-organoid.org/upload/pdf/organoid-2022-2-e14.pdf
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