Vindoline Inhibits RANKL-Induced Osteoclastogenesis and Prevents Ovariectomy-Induced Bone Loss in Mice

Osteolytic bone diseases, for example postmenopausal osteoporosis, arise from the imbalances between osteoclasts and osteoblasts in the bone remodeling process, whereby osteoclastic bone resorption greatly exceeds osteoblastic bone formation resulting in severe bone loss and deterioration in bone st...

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Detalhes bibliográficos

Principais autores:	Yunfei Zhan, Jiamin Liang, Kun Tian, Zhigang Che, Ziyi Wang, Xue Yang, Yuangang Su, Xixi Lin, Fangming Song, Jinmin Zhao, Jiake Xu, Qian Liu, Bo Zhou
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2020-01-01
coleção:	Frontiers in Pharmacology
Assuntos:	vindoline MAPK osteoclast osteoporosis NFATc1
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fphar.2019.01587/full
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