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Synthesis and Evaluation of Novel Norfloxacin Isonitrile <sup>99m</sup>Tc Complexes as Potential Bacterial Infection Imaging Agents

To develop potential technetium-99m single-photon emission computed tomography (SPECT) imaging agents for bacterial infection imaging, the novel norfloxacin isonitrile derivatives CN4NF and CN5NF were synthesized and radiolabeled with a [<sup>99m</sup>Tc][Tc(I)]<sup>+</sup> core to obtain [<sup>99m<...

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Principais autores: Si’an Fang, Yuhao Jiang, Di Xiao, Xuran Zhang, Qianqian Gan, Qing Ruan, Junbo Zhang
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-04-01
Serier:Pharmaceutics
Fag:
norfloxacin
isonitriles
quinolones
technetium-99m
infection imaging
Online adgang:https://www.mdpi.com/1999-4923/13/4/518
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