QR-Code

Skeletal muscle cell protein dysregulation highlights the pathogenesis mechanism of myopathy-associated p97/VCP R155H mutations

p97/VCP, a hexametric member of the AAA-ATPase superfamily, has been associated with a wide range of cellular protein pathways, such as proteasomal degradation, the unfolding of polyubiquitinated proteins, and autophagosome maturation. Autosomal dominant p97/VCP mutations cause a rare hereditary mul...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Anna Luzzi, Feng Wang, Shan Li, Michelina Iacovino, Tsui-Fen Chou
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2023-08-01
Schriftenreihe:Frontiers in Neurology
Schlagworte:
VCP/p97
IBMPFD/ALS
iPSCs
skeletal muscle
myopathy
R155H mutation
Online-Zugang:https://www.frontiersin.org/articles/10.3389/fneur.2023.1211635/full
Tags: Tag hinzufügen
Keine Tags, Fügen Sie das erste Tag hinzu!

Ähnliche Einträge