Chloroquine inhibits salinomycin-induced autophagy for collaborative anticancer effect in breast cancer

Introduction: Breast cancer (BC) presents significant morbidity and mortality challenges. Autophagy plays a contradictory role in BC. The chemotherapeutic agent salinomycin exhibits anticancer effects, but its effectiveness is limited by over-activation of autophagy. This study aimed to investigate...

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Hauptverfasser: Xiaoting Yang, Zhan Jin, Gao Chen, Gaobo Hu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Tabriz University of Medical Sciences 2025-05-01
Schriftenreihe:BioImpacts
Schlagworte:
breast cancer
salinomycin
chloroquine
autophagy
pi3k/akt/mtor signaling pathway
Online Zugang:https://bi.tbzmed.ac.ir/PDF/bi-15-30821.pdf
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