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DNA methylation age is not affected in psoriatic skin tissue

Abstract Background Psoriasis (Ps) is a common chronic inflammatory skin disease. The keratinocytes of psoriatic skin defy normal apoptosis and exhibit active cell proliferation. Aberrant DNA methylation (DNAm) has been suggested relevant through regulating the expression of Ps susceptibility genes....

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Principais autores: Changbing Shen, Leilei Wen, Randy Ko, Jing Gao, Xue Shen, Xianbo Zuo, Liangdan Sun, Yi-Hsiang Hsu, Xuejun Zhang, Yong Cui, Meng Wang, Fusheng Zhou
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2018-12-01
coleção:Clinical Epigenetics
Assuntos:
Psoriasis
DNA methylation age
Skin tissue
Chinese Han population
Acesso em linha:http://link.springer.com/article/10.1186/s13148-018-0584-y
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