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Investigation of the myelin-amyloid interplay in Alzheimer’s disease: insights from novel dsCMA imaging in mouse and human brains

Abstract Myelin deterioration impairs neural communication and may contribute to neurodegenerative diseases such as Alzheimer’s disease (AD). However, the spatiotemporal relationship between myelin degeneration and AD pathology remains unclear. We developed a novel imaging method—double-scan Cyto- a...

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Principais autores: Hanpeng Xu, Sumit Nanda, Jiandong Sun, Mitchell Rudd, Lin Gou, Haley Marks, Christopher K. Williams, Shino Magaki, Harry V. Vinters, Houri Hintiryan, Hong-Wei Dong
Format: Artigo
Jezik:Inglês
Izdano: BMC 2026-05-01
Serija:Acta Neuropathologica Communications
Online dostop:https://doi.org/10.1186/s40478-026-02317-8
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