Astrocytes produce nitric oxide via nitrite reduction in mitochondria to regulate cerebral blood flow during brain hypoxia

Summary: During hypoxia, increases in cerebral blood flow maintain brain oxygen delivery. Here, we describe a mechanism of brain oxygen sensing that mediates the dilation of intraparenchymal cerebral blood vessels in response to reductions in oxygen supply. In vitro and in vivo experiments conducted...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Isabel N. Christie, Shefeeq M. Theparambil, Alice Braga, Maxim Doronin, Patrick S. Hosford, Alexey Brazhe, Alexander Mascarenhas, Shereen Nizari, Anna Hadjihambi, Jack A. Wells, Adrian Hobbs, Alexey Semyanov, Andrey Y. Abramov, Plamena R. Angelova, Alexander V. Gourine
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2023-12-01
Цуврал:	Cell Reports
Нөхцлүүд:	CP: Neuroscience CP: Metabolism
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S2211124723015267
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!