MicroRNA-383-5p regulation of NADPH oxidase 4 alleviates hemorrhagic transformation and improves acute outcomes after endovascular recanalization in acute ischemic stroke

BackgroundHemorrhagic transformation (HT) following reperfusion therapy is associated with poor outcomes in patients with acute ischemic stroke. Here, we determined the role of microRNA-383-5p (miR-383-5p) in alleviating HT-associated injury using models of middle cerebral artery occlusion (MCAO) an...

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Bibliografski detalji

Glavni autori:	Qiu-Yi Jiang, Wang Qin, Jin-Kun Zhuang, Ze-Xin Chen, Qian-Yu Chen, Chang-Luo Li, Zhong-Song Shi
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2026-06-01
Serija:	Frontiers in Immunology
Teme:	acute ischemic stroke hemorrhagic transformation inflammation microRNA NOX4 oxygen-glucose deprivation reoxygenation
Online pristup:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1870493/full
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