LncRNA H19 governs mitophagy and restores mitochondrial respiration in the heart through Pink1/Parkin signaling during obesity

Abstract Maintaining proper mitochondrial respiratory function is crucial for alleviating cardiac metabolic disorders during obesity, and mitophagy is critically involved in this process. Long non-coding RNA H19 (H19) is crucial for metabolic regulation, but its roles in cardiac disorders, mitochond...

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Principais autores:	Shao-Hua Wang, Xiao-Lin Zhu, Fei Wang, Si-Xu Chen, Zhi-Teng Chen, Qiong Qiu, Wen-Hao Liu, Mao-Xiong Wu, Bing-Qing Deng, Yong Xie, Jing-Ting Mai, Ying Yang, Jing-Feng Wang, Hai-Feng Zhang, Yang-Xin Chen
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Nature Publishing Group 2021-05-01
סדרה:	Cell Death and Disease
גישה מקוונת:	https://doi.org/10.1038/s41419-021-03821-6
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