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Calcium overload via PVT1 reprograms neutrophil fate and constrains gastric cancer progression

Abstract Background The aberrant upregulation of PVT1 in gastric cancer (GC) has emerged as a critical molecular marker, while its mechanism of remodeling the tumor microenvironment (TME) through metabolic regulation remains unclear. This study aims to unveil the novel mechanism by which PVT1 regula...

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Bibliografiske detaljer
Principais autores: Dong Wang, Yunlong Li, Xiaoyu Peng, Lulu Zhang, Ying Zhang, Xue Guan, Xiao Liang, Songbin Fu, Jingcui Yu
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-08-01
Serier:Journal of Translational Medicine
Fag:
Online adgang:https://doi.org/10.1186/s12967-025-06912-6
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