Pharmacology and metabolomic reveal Polysaccharides from polygonatum sibiricum ameliorate the diabetic osteoporosis in zebrafish

Abstract Background Previous studies found that Polygonatum sibiricum polysaccharide (PSP) exhibited anti-inflammatory and anti-oxidative effects on type 2 diabetes (T2DM). However, the roles and detailed mechanisms of PSP on the anti-diabetic osteoporosis are still poorly defined. The purpose of th...

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Autori principali: Ziping Chen, Na Li, Zhou Zhou, Lin Zhu, Kai Wang, Shijin Chen, Quan Gu, Yujun Liu, Kefeng Zhai, Shuwen Xu
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2025-07-01
Serie:BMC Complementary Medicine and Therapies
Soggetti:
Anti-diabetic
Metabolomics
Osteoporosis
Polysaccharide
Zebrafish
Accesso online:https://doi.org/10.1186/s12906-025-04978-9
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