Reverse genetics in Candida albicans predicts ARF cycling is essential for drug resistance and virulence.

Candida albicans, the major fungal pathogen of humans, causes life-threatening infections in immunocompromised individuals. Due to limited available therapy options, this can frequently lead to therapy failure and emergence of drug resistance. To improve current treatment strategies, we have combine...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Elias Epp, Ghyslaine Vanier, Doreen Harcus, Anna Y Lee, Gregor Jansen, Michael Hallett, Don C Sheppard, David Y Thomas, Carol A Munro, Alaka Mullick, Malcolm Whiteway
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Public Library of Science (PLoS) 2010-02-01
Schriftenreihe:	PLoS Pathogens
Online-Zugang:	https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1000753&type=printable
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