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Activity of Hydrophilic, Biocompatible, Fluorescent, Organic Nanoparticles Functionalized with Purpurin-18 in Photodynamic Therapy for Colorectal Cancer

Photodynamic therapy (PDT) is a clinically approved, non-invasive therapy currently used for several solid tumors, triggering cell death through the generation of reactive oxygen species (ROS). However, the hydrophobic nature of most of the photosensitizers used, such as chlorins, limits the overall...

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Principais autores: Rayan Chkair, Justine Couvez, Frédérique Brégier, Mona Diab-Assaf, Vincent Sol, Mireille Blanchard-Desce, Bertrand Liagre, Guillaume Chemin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2024-09-01
coleção:Nanomaterials
Assuntos:
colorectal cancer
photodynamic therapy
purpurin-18
nanocarriers
FONPs
apoptosis
Acesso em linha:https://www.mdpi.com/2079-4991/14/19/1557
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