Growth cone MKK7 mRNA targeting regulates MAP1b-dependent microtubule bundling to control neurite elongation.
Local mRNA translation in neurons has been mostly studied during axon guidance and synapse formation but not during initial neurite outgrowth. We performed a genome-wide screen for neurite-enriched mRNAs and identified an mRNA that encodes mitogen-activated protein kinase kinase 7 (MKK7), a MAP kina...
Furkejuvvon:
| Váldodahkkit: | , , , , , , , , |
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| Materiálatiipa: | Artigo |
| Giella: | Inglês |
| Almmustuhtton: |
Public Library of Science (PLoS)
2012-01-01
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| Ráidu: | PLoS Biology |
| Liŋkkat: | https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.1001439&type=printable |
| Fáddágilkorat: |
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