Adenosine A1 Receptor Agonist 2-chloro-N6-cyclopentyladenosine and Hippocampal Excitability During Brain Development in Rats

Objective: The adenosinergic system may influence excitability in the brain. Endogenous and exogenous adenosine has anticonvulsant activity presumably by activating A1 receptors. Adenosine A1 receptor agonist 2-chloro-N6-cyclopentyladenosine (CCPA) may thus bolster anticonvulsant effects, but its ac...

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Detalhes bibliográficos

Principais autores:	Petr Fabera, Martina Parizkova, Libor Uttl, Katerina Vondrakova, Hana Kubova, Grygoriy Tsenov, Pavel Mares
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2019-06-01
coleção:	Frontiers in Pharmacology
Assuntos:	adenosine receptor agonist development hippocampus epileptic afterdischarges rat
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fphar.2019.00656/full
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