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Design and synthesis of phenolic Mannich base hydrazide-hydrazone hybrids: in vitro antioxidant activity, cytotoxicity and in silico studies

Vanillic acid, a naturally occurring phenolic compound, is well known for its antioxidant properties. In this study, a series of vanillic acid-based Mannich base hydrazide derivatives and their corresponding hydrazones were synthesized, and characterized using different spectroscopic techniques. The...

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Principais autores: K. Nagaraj Pai, Navas Shereef Ellyan, M. Mallikarjun, Rachel Alveera Menezes, Angel Treasa Alex, Ananda Kulal, K. Subrahmanya Bhat
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2026-07-01
Serier:Results in Chemistry
Fag:
Hydrazide-hydrazones
Mannich base
Antioxidant activity
Cytotoxicity
Drug-likeliness
Online adgang:http://www.sciencedirect.com/science/article/pii/S2211715626004558
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