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Diet-Induced Obesity and NASH Impair Disease Recovery in SARS-CoV-2-Infected Golden Hamsters

Obese patients with non-alcoholic steatohepatitis (NASH) are prone to severe forms of COVID-19. There is an urgent need for new treatments that lower the severity of COVID-19 in this vulnerable population. To better replicate the human context, we set up a diet-induced model of obesity associated wi...

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Principais autores: François Briand, Valentin Sencio, Cyril Robil, Séverine Heumel, Lucie Deruyter, Arnaud Machelart, Johanna Barthelemy, Gemma Bogard, Eik Hoffmann, Fabrice Infanti, Oliver Domenig, Audrey Chabrat, Virgile Richard, Vincent Prévot, Ruben Nogueiras, Isabelle Wolowczuk, Florence Pinet, Thierry Sulpice, François Trottein
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-09-01
coleção:Viruses
Assuntos:
obesity
non-alcoholic steatohepatitis
coronavirus disease 2019
SARS-CoV-2
hamster
Acesso em linha:https://www.mdpi.com/1999-4915/14/9/2067
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