The core Cas1 protein of CRISPR-Cas I-B in Leptospira shows metal-tunable nuclease activity

Leptospira interrogans serovar Copenhageni strain Fiocruz L1-130 is the causative agent of leptospirosis in animals and humans. This organism carries a functional cas1 gene classified under CRISPR-Cas I-B. In this study, using various nuclease assays and bioinformatics analysis, we report that the r...

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Bibliografische Detailangaben

Hauptverfasser:	Bhuvan Dixit, Aman Prakash, Pankaj Kumar, Prerana Gogoi, Manish Kumar
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2021-12-01
Schriftenreihe:	Current Research in Microbial Sciences
Schlagworte:	Leptospira Nucleases Cas protein CRISPR-Cas DNase
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2666517421000407
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