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Spatiotemporal Expression Inversion of <i>CYP11A1</i> in the HPO Axis and Its Regulation of Granulosa Cell Proliferation via the PI3K/AKT/mTOR Pathway in Wuding Chickens

Broodiness in poultry represents a major bottleneck for reproductive performance, governed by complex remodeling of the hypothalamic-pituitary-ovarian (HPO) axis. CYP11A1, the rate-limiting enzyme in steroidogenesis, is essential for hormone synthesis; however, its spatiotemporal dynamics within the...

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Bibliografiske detaljer
Principais autores: Enmin Wan, Wei Zhu, Cailing Wang, Jinda Li, Xinyang Fan, Yongwang Miao
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2026-02-01
Serier:Animals
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Online adgang:https://www.mdpi.com/2076-2615/16/4/657
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