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Bruton’s tyrosine kinase inhibitors in the treatment of primary central nervous system lymphoma: A mini-review

Primary central nervous system lymphoma (PCNSL) is a highly aggressive brain tumor with poor prognosis if no treatment. The activation of the NF-κB (nuclear factor kappa-B) is the oncogenic hallmark of PCNSL, and it was driven by B cell receptor (BCR) and Toll-like receptor (TLR) signaling pathways....

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Autors principals: Jing Shen, Jinghua Liu
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2022-11-01
Col·lecció:Frontiers in Oncology
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fonc.2022.1034668/full
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