Expanding the DNA editing toolbox: Novel lambda integrase variants targeting microalgal and human genome sequences.
Recombinase enzymes are extremely efficient at integrating very large DNA fragments into target genomes. However, intrinsic sequence specificities curtail their use to DNA sequences with sufficient homology to endogenous target motifs. Extensive engineering is therefore required to broaden applicabi...
-д хадгалсан:
| Үндсэн зохиолчид: | , , , , , , , , |
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| Формат: | Artigo |
| Хэл сонгох: | Inglês |
| Хэвлэсэн: |
Public Library of Science (PLoS)
2024-01-01
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| Цуврал: | PLoS ONE |
| Онлайн хандалт: | https://doi.org/10.1371/journal.pone.0292479 |
| Шошгууд: |
Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!
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