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The Runx transcriptional co-activator, CBFβ, is essential for invasion of breast cancer cells

<p>Abstract</p> <p>Background</p> <p>The transcription factor Runx2 has an established role in cancers that metastasize to bone. In metastatic breast cancer cells Runx2 is overexpressed and contributes to the invasive capacity of the cells by regulating the expression of several invasion genes. CBFβ...

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Auteurs principaux: Lopez-Camacho Cesar, Deng Wensheng, Mendoza-Villanueva Daniel, Shore Paul
Format: Artigo
Langue:Inglês
Publié: BMC 2010-06-01
Collection:Molecular Cancer
Accès en ligne:http://www.molecular-cancer.com/content/9/1/171
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