LRP5 promotes adipose progenitor cell fitness and adipocyte insulin sensitivity
Abstract Background WNT signaling plays a key role in postnatal bone formation. Individuals with gain-of-function mutations in the WNT co-receptor LRP5 exhibit increased lower-body fat mass and potentially enhanced glucose metabolism, alongside high bone mass. However, the mechanisms by which LRP5 r...
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| Principais autores: | , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Portfolio
2025-02-01
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| coleção: | Communications Medicine |
| Acesso em linha: | https://doi.org/10.1038/s43856-025-00774-1 |
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