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Loss of heat shock factor 1 promotes hepatic stellate cell activation and drives liver fibrosis

Abstract Liver fibrosis is an aberrant wound healing response that results from chronic injury and is mediated by hepatocellular death and activation of hepatic stellate cells (HSCs). While induction of oxidative stress is well established in fibrotic livers, there is limited information on stress‐m...

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Bibliografiske detaljer
Principais autores: Asmita Choudhury, Anuradha Ratna, Arlene Lim, Rebecca M. Sebastian, Christopher L. Moore, Aveline A. Filliol, Jacob Bledsoe, Chengkai Dai, Robert F. Schwabe, Matthew D. Shoulders, Pranoti Mandrekar
Format: Artigo
Sprog:Inglês
Udgivet: Wolters Kluwer Health/LWW 2022-10-01
Serier:Hepatology Communications
Online adgang:https://doi.org/10.1002/hep4.2058
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