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Posterior Ciliary Artery Contraction by Bradykinin Receptor Subtypes and Implications for Retinal Blood Flow Dysfunction

Background: Low retinal blood flow and/or vasospasm represent major risk factors for the development of glaucomatous optic neuropathy (GON), a potentially blinding eye disease. Bradykinin (BK), a nonapeptide, is endogenously produced and released, which can cause smooth muscles to...

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Principais autores: Najam A. Sharif, Sunny E Ohia, Madhura Kulkarni-Chitnis, Anthonia Okolie, Saima D. Chaudhry, Ya Fatou Njie-Mbye
Format: Artigo
Sprog:Inglês
Udgivet: IMR Press 2025-09-01
Serier:Frontiers in Bioscience-Elite
Fag:
posterior ciliary artery
blood vessel contraction
blood flow
oxidative stress
bradykinin
retina damage
glaucomatous optic neuropathy
glaucoma
Online adgang:https://www.imrpress.com/journal/FBE/17/3/10.31083/FBE37072
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