Modification of Glyceraldehyde-3-Phosphate Dehydrogenase with Nitric Oxide: Role in Signal Transduction and Development of Apoptosis

This review focuses on the consequences of GAPDH <i>S</i>-nitrosylation at the catalytic cysteine residue. The widespread hypothesis according to which <i>S</i>-nitrosylation causes a change in GAPDH structure and its subsequent binding to the Siah1 protein is considered in detail. It is assumed tha...

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Detalhes bibliográficos

Principais autores:	Vladimir I. Muronetz, Maria V. Medvedeva, Irina A. Sevostyanova, Elena V. Schmalhausen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2021-11-01
Colecção:	Biomolecules
Assuntos:	glyceraldehyde-3-phosphate dehydrogenase <i>S</i>-nitrosylation protein–protein interactions oxidation sulfenic acid NO
Acesso em linha:	https://www.mdpi.com/2218-273X/11/11/1656
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