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Avenanthramide C mitigates cisplatin-induced hippocampal neurotoxicity and cognitive impairment in rats via suppression of neuroinflammation and neuronal apoptosis

IntroductionCisplatin (CP)-induced cognitive impairment, commonly referred to as chemobrain, affects a substantial proportion of patients with cancer and currently lacks an effective pharmacological treatment. This condition is closely linked to neuroinflammation. Avenanthramide C (AVN-C), a bioacti...

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Autor principal: Maha Abdulrahman Aldubayan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2025-11-01
Colecção:Frontiers in Pharmacology
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fphar.2025.1706224/full
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