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Combined mRNA expression levels of members of the urokinase plasminogen activator (uPA) system correlate with disease-associated survival of soft-tissue sarcoma patients

<p>Abstract</p> <p>Background</p> <p>Members of the urokinase-type plasminogen activator (uPA) system are up-regulated in various solid malignant tumors. High antigen levels of uPA, its inhibitor PAI-1 and its receptor uPAR have recently been shown to be associated with poor prognosis in soft-tissue...

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Principais autores: Luther Thomas, Eckert Alexander W, Füssel Susanne, Lautenschläger Christine, Bache Matthias, Kappler Matthias, Greither Thomas, Kotzsch Matthias, Magdolen Viktor, Baretton Gustavo, Würl Peter, Taubert Helge
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2011-06-01
Serier:BMC Cancer
Online adgang:http://www.biomedcentral.com/1471-2407/11/273
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